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National Heart, Lung and Blood Institute (NHLBI)


Denise Bonds, MD, MPH
CCOR Deputy Project Officer
Program Director in the Clinical Applications and Prevention Branch, Division of Cardiovascular Sciences


6701 Rockledge Drive, Building 2
Suite 10018
Bethesda, MD 20892 


Mission Statement

The National Heart, Lung and Blood Institute (NHLBI) provides global leadership for a research, training, and education program to promote the prevention and treatment of heart, lung, and blood diseases and enhance the health of all individuals so that they can live longer and more fulfilling lives.
The NHLBI stimulates basic discoveries about the causes of disease, enables the translation of basic discoveries into clinical practice, fosters training and mentoring of emerging scientists and physicians, and communicates research advances to the public. It creates and supports a robust, collaborative research infrastructure in partnership with private and public organizations, including academic institutions, industry, and other government agencies. The Institute collaborates with patients, families, health care professionals, scientists, professional societies, patient advocacy groups, community organizations, and the media to promote the application of research results and leverage resources to address public health needs. The NHLBI also collaborates with international organizations to help reduce the burden of heart, lung, and blood diseases worldwide.

Health Services and Outcomes Research at NHLBI

“The NHLBI Strategic Plan highlights the need for 2 stages of translation—moving basic knowledge into clinical evidence and moving clinical evidence into clinical practice and public policy.” Nabel EG, Lauer MS. J Am Coll Cardiol. 2009;53(12):1082-3

The Centers for Cardiovascular Outcomes Research focus on exactly this, the movement of clinical evidence into practice and public policy. These centers support three challenges in the NHLBI Strategic Plan:

    • Challenge 3.1.c. Develop and evaluate interventions to improve patient, provider and health-care system behavior and performance to enhance quality of care and health outcomes
    • Challenge 3.2. Identify cost-effective approaches for prevention, diagnosis and treatment
    • Challenge 3.3.b. Develop approaches to increase use of evidence-based guidelines by individuals, communities, health-care providers and especially by populations with disproportionate disease burden

In addition to the strategic plan, working groups and workshops inform research efforts at NHLBI. The Outcomes Research in Cardiovascular Disease (CVD) Outcomes working group was convened in 2004, and remains pertinent today. The Centers for Cardiovascular Outcomes Research are products of this working group report. Other workshops and working groups that support the need for health services and outcomes research include the following: Outcomes Research in Cardiovascular Imaging; Improving Delivery of Preventive Interventions in Clinical Practice; CVD Prevention in High Risk Communities; NHLBI CVD Comparative Effectiveness Research Workshop; Improving Hospital-to-Home Transitions and Disease Management. The reports from these workshops and others can be found online:

The NHLBI does release occasional funding announcements targeted at health services and outcomes research. For a complete listing of current funding announcements, please see the NHLBI website: ( However, most of the health services and outcomes research that NHLBI funds does not come through specific funding announcements, but rather from investigator-initiated applications submitted through existing NHLBI parent grant announcements. If you are interested in submitting an application, contact a Program Director at NHLBI who will assist you with the process.


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